Cannabidiol (CBD) is a chemical found in the Cannabis sativa plant, often referred to as hemp or marijuana. More than eighty chemicals, referred to as cannabinoids, have been found in the Cannabis sativa plant. The House of Commons in Canada sanctioned and accredited the C-45 bill, commonly known as Cannabis Act. The act was passed back on 27th November 2017, and was later implemented in the year 2018, since then the purchase, possession and intake of Cannabis and its products was no longer a crime in Canada. Since CBD has been researched as a new drug, it cannot be legally added to dietary and food supplements.
However, there are some other products labeled as dietary complements available on the market that have cannabidiol. The quantity of cannabidiol available in these dietary products is not normally shown accurately on the product label. CBD is mainly used for epilepsy (seizure disorder). The product can also be used to relieve pain, anxiety, dystonia (muscle disorder), Crohn illness, and Parkinson disease, among other health conditions.
How it works
CBD has impacts on the brain. But the precise cause for these impacts is not yet proven. Nevertheless, CBD seems to effectively prevent the breakdown of a certain substance in the brain affects mental function, pain, and mood. Hindering the breakdown of this substance and raising its levels in the bloodstream seems to decrease symptoms of psychotic related to conditions like schizophrenia. Additionally, CBD has been proven to reduce nervousness and distress.
Positive CBD Effect
Since 2900 B.C, Marijuana products have been utilized as pain relievers. Recently, researchers have learned that some substances of marijuana, such as CBD, are effective for their pain-relieving impacts. The body of a human being has a specialized system often known as ECS (endocannabinoid system), which is used in controlling a range of functions such as the response of the immune system, pain, appetite, and sleep. The body stem generates endocannabinoids, which function as neurotransmitters that bind to CBD receivers in the nervous system. According to research, CBD products might assist in relieving chronic pain by facilitating the ECS receptor action, interacting with neurotransmitters, and decreasing inflammation.
For instance, a certain study in rats showed that the injections of CBD reduced the response of pain to surgical incisions. Also, another study in rats showed that oral CBD use greatly decreased inflammation and sciatic nerve pain.
Many human studies have shown that CBD is efficient in relieving pain associated with arthritis and multiple sclerosis. Sativex (oral spray), a derivative of CBD, is used by Canadian residents to relieve pain associated with multiple sclerosis. A certain study of forty-seven individuals suffering from multiple sclerosis tested the impacts of Sativex consumption for four weeks. The participants faced improvements in muscle spasms, walking, and pain. However, the research did not involve any control team, and placebo impacts cannot be driven out.
Also, another research showed that Sativex greatly improved sleep quality and relieved pain during movement and while at rest in fifty-eight individuals who had rheumatoid arthritis.
Acne refers to a certain skin disorder that affects over nine percent of the world’s population. The skin condition is assumed to be resulting from several factors such as bacteria, genetics, sebum overproduction, underlying inflammation, and an oily secretion produced by sebaceous skin glands. According to recent scientific research, CBD oil products may assist in acne treatment because of their anti-inflammatory properties and capacity to lower the generation of sebum.
Certain test-tube research showed that CBD oils prevent sebaceous gland cells from excessive sebum production, generated anti-inflammatory properties, and prevented pro-acne agent activation. Additionally, another research produced similar results, therefore concluding that CBD oils might be a convenient and secure way to heal acne due to their anti-inflammatory properties.
Reduces depression and anxiety
Depression and anxiety are the most common emotional disorders that cause devastating effects on well-being and health. According to WHO, depression is ranked as the sole major contributor to disability globally, while anxiety appears at the sixth rank. Depression and anxiety are normally treated with medicinal drugs, which can lead to several side effects such as sexual dysfunction, drowsiness, headache, insomnia, and agitation. What is more, medicinal drugs, including benzodiazepines, could be addictive and might cause drug and substance abuse.
The CBD oil products have shown promise as the cure for both anxiety and depression, leading most individuals who suffer from these disorders to become more interested in this natural treatment approach.
According to certain Brazilian research, fifty-seven people received either a placebo for ninety minutes or oral CBD treatment before undergoing a replicated public speaking evaluation. The study found out that a three hundred milligram dose of CBD was the most efficient at greatly decreasing depression and anxiety during the public speaking test. On the other hand, the placebo, a 600-mg dose, and a 150-mg dose of CBD had little to no impact on depression and anxiety.
Also, CBD oil products have been utilized to securely treat anxiety and insomnia that affect kids with post-traumatic distress. It has also displayed antidepressant-like impacts in several animal studies. The properties are associated with the CBD'S capacity to take action on the brain's receivers for serotonin, often known as a neurotransmitter that controls social behavior and mood.
Benefits heart health
Recent studies have related CBD with a number of benefits for the blood circulatory system and blood, including the capability to reduce high blood pressure. The situation of high blood pressure is related to greater risks of several well-being conditions such as metabolic syndrome, heart attack, and stroke.
Research has indicated that CBD might be able to assist in lowering high blood pressure. Recent research that included nine healthy males treated with a 600-mg dosage of CBD found out that the dose lowered resting blood pressure, as opposed to placebo. This research also offered the makes stress tests that usually raise blood pressure. Remarkably, a single dose of CBD made the males experience a lower blood pressure rise than usual in response to the stress tests.
According to researchers, the anxiety- and stress-reducing qualities of CBD oil products are responsible for their capability to help in keeping low levels of blood pressure. Also, many animal studies have shown that CBD can help reduce the cell and inflammation death related to heart disease because of its stress-reducing and powerful antioxidant qualities.
For instance, one research found out using CBD for heart disease treatment relieved stress and protected heart damage.
Alleviates cancer-related signs and symptoms
CBD can assist in alleviating cancer–related symptoms and negative effects related to the treatment of cancer, including pain, vomiting, and nausea. Recent research looked at the impacts of CBD in one hundred and seventy-seven individuals with cancer-related suffering who never experienced pain relief even after medication. The participants noticed a great pain relief after consuming the CBD oil.
CBD can also help in the reduction of chemotherapy-induced vomiting and nausea, which are the most common chemo-therapy-associated side effects for individuals with cancer. Although there are drugs that reduce these discomforting signs and symptoms, they can sometimes be ineffectual, leading most individuals to look for alternatives.
Another research that involved sixteen individuals undergoing chemotherapy treatment showed CBD administered through oral spray lowered chemotherapy-related vomiting and nausea compared to just pharmaceutical treatment. Other studies involved animal and test tubes, which found that CBD can have anti-cancer qualities. For instance, one test-tube research showed that concentrated CBD facilitated the death of human breast cancer cells. Also, another research found that CBD reduced the spread of destructive mice breast cancer cells. Nevertheless, these are just test-tube and animal studies, which means that they can only show what might effectively work in human beings. More research on people is need before conclusions can be drawn.
Have Neuroprotective qualities
Studies have shown the CBD's capability to take action on the ECS, and other brain systems might be beneficial for those experiencing neurological disorders. Actually, one of the most proven benefits of CBD products is in treating the most common neurological disorders, including multiple sclerosis and epilepsy. Although the study in this field is reasonably new, a number of studies have revealed promising findings.
Sativex, a spray administered through the mouth consisting of CBD derivatives, has been recently proven to be an effective and safe way of reducing muscle spasticity in individuals experiencing multiple sclerosis. Research showed that Sativex inhibited spasms in seventy-five percent of two hundred and seventy-six individuals with multiple sclerosis who had muscle spasticity that resisted medications. Another research gave two hundred and fourteen individuals with serious epilepsy 0.9g to 0.3g of CBD per pound (two to five g-kg) of body system’s weight. Their seizures were minimized by a significant median of nearly thirty-seven percent.
More research showed that CBD products greatly minimized the seizure action in kids with Dravet syndrome, a complicated epilepsy disorder in children, better than a placebo. Nevertheless, it is crucial to note that individuals in all these studies faced adverse reactions related to CBD treatment, like fatigue, fever, and convulsions. Also, CBD has also been proven to have potential efficiency in treating a number of other neurological ailments. For instance, numerous studies have found that CBD treatment improved sleep quality and quality of life for individuals with Parkinson’s illness.
Additionally, test-tube and animal studies have found that CBD treatment decreases inflammation and assist in preventing neurodegeneration-related Alzheimer's illness. In certain long-term research, scientists gave CBD oil to mice inherently predisposed to Alzheimer's ailment, finding that the CBD assisted in preventing cognitive decline.
Other potential CBD benefits include:
CBD has been proven to help in treating several health conditions other than the ones mentioned above. Although more research is required, CBD oil products are thought to offer the benefits listed below:
- Prevention of diabetes: in diabetic mice, CBD treatment minimized the diabetes incidence by fifty-six percent and greatly minimized inflammation.
- Anti-tumor properties: in animal and test-tube studies, CBD has shown anti-tumor properties. For instance, it has been thought to be preventing the spread of lung, colon, brain, and breast cancer in animals.
- Treatment of drug and substance abuse: CBD has been proven to regulate circuits in the brain associated with drug and substance addiction. In the study that involved rats, CBD oil has been shown to lower heroin-seeking character and morphine dependence.
- Antipsychotic properties: research shows that CBD can be effective in individuals experiencing schizophrenia and other emotional disorders by minimizing psychotic symptoms.
Negative CBD effect
Generally, CBD oil gives a promise as a potential treatment for the most common diseases. Studies have found that CBD effect might be efficient in relieving stress, reducing acne, depression, anxiety, and stress. Also, it has shown potential anti-seizure and anti-inflammatory qualities, which means that it may be a potential cure for common seizure problems. Although many benefits surround CBD, there are negative effects that you ought to be aware of. Below is a list of some of the common CBD negative effects and what you can do to handle them.
1. Dry mouth
Dry mouth refers to a common negative impact that is experienced by individuals using any type of cannabinoid product, including CBD oils. The situation of dryness in the mouth may happen if cannabinoid products are vaped, smoked, or consumed. You might realize that you have a dry mouth while utilizing CBD due to how CBD interacts with the ECS. The endocannabinoid system has receivers in the salivary glands; therefore, when activated, the process of saliva secretion may be affected.
Based on one research, the submandibular gland that generates more than sixty percent of saliva has CBD receptors. Additionally, Anandamide, which is an ECS in the body system, is associated with the situation of dryness of the mouth. This occurs when the ECS interacts with submandibular receivers, which block the nervous system signals that indicate the gland responsible for generating saliva.
- Interaction with medicinal drugs
Individuals taking any type of medicinal drug for the underlying health condition have to consult with their personal doctor before taking CBD. This is based on a certain CBD effect study that showed that the compound negatively impacts the process of drug metabolism in the liver.
Cannabinoid impedes the action of particular liver enzymes, the cytochrome P450 system, which breaks down the medicinal drugs. If there are other pharmaceutical drugs, the cannabinoid might actually improve enzyme action, which can be very destructive. This means that any medicinal drug that utilizes the CYP450 enzyme systems to digest might harmfully interact with CBD. The most common drugs that interact with CBD include:
- Calcium channel blockers
In order to protect your health, normalize consulting your doctor to get recommendations on how and when to use CBD products. This way, you are aware of any side effects and how to prevent them as required.
CBD is a product that exhibits relaxing and calming properties. Although it typically does not lead to the experience of drowsiness or tiredness, there is a possibility. Just like any other compound, how CBD affects your normal functioning of the body might differ from how it interacts with somebody else. For example, some individuals may experience a wake-inducing impact immediately after taking CBD- this makes them more energetic and alert. While for some people, the CBD triggers an opposite reaction, which makes users feel tired and drowsy.
If you realize that you are experiencing drowsiness or tiredness after getting CBD treatment, avoid operating any massive machinery or driving. Since CBD products affect your energy, it is important to protect your safety and health as well as the health of the ones near you.
- Lightheadedness and dizziness
This may be a very rare negative impact on most people. However, it is possible that you might feel lightheaded or dizzy after getting CBD treatment. This effect is typically temporary and may be relieved by taking any caffeinated drink, including coffee. This will enable your body to gain its balance back.
How to reduce the CBD side effect
One of the first precautions you should take while on CBD treatment is to use the right dosage. If it is your first time, you will need to start with the lowest amount possible. You can get different CBD products available in as low doses as 10mg and 5mg.
Secondly, one of the greatest ways to minimize CBD side effects is to only go for high-quality products. Do not buy the CBD items sold at local convenience places such as gas stations. You can buy effective CBD products online.
CBD has been researched for its promising responsibility of minimizing symptoms of a number of health conditions, including heart disease, acne, depression, and anxiety. For those suffering from cancer, it can even offer a natural option for symptom and pain relief. Studies on the promising health benefits of CBD are still ongoing, which means new therapeutic applications for this natural treatment are sure to be learned. While studies have shown that CBD provides all sorts of health benefits, there are still side effects that you should be cautious of. If you notice any of the aforementioned side effects, lower your prescription or consult your medical practitioner.